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Gapless comparative genomics reveals effector landscape and adaptive selection signatures in Plasmodiophora brassicae

doi: 10.1016/j.jgg.2026.06.011
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This research was supported by the Introduction of High-level Overseas Talents Program in Hebei Province (E2020100004) and S&T Program of Hebei (246Z6302G).

  • Received Date: 2026-02-28
  • Accepted Date: 2026-06-22
  • Rev Recd Date: 2026-06-22
  • Available Online: 2026-06-29
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  • Frantzeskakis, L., Kusch, S., Panstruga, R., 2019. The need for speed: compartmentalized genome evolution in filamentous phytopathogens. Mol. Plant Pathol. 20, 3-7.
    Javed, M.A., Mukhopadhyay, S., Normandeau, E., Brochu, A.-S., Perez-Lopez, E., 2024. Telomere-to-telomere genome assembly of the clubroot pathogen Plasmodiophora brassicae. Genome Biol. Evol. 16, evae122.
    Javed, M.A., Schwelm, A., Zamani-Noor, N., Salih, R., Vano, M.S., Wu, J., Garcia, M.G., Heick, T.M., Luo, C., Prakash, P., et al., 2022. The clubroot pathogen Plasmodiophora brassicae: a profile update. Mol. Plant Pathol. 24, 89-106.
    Li, P., Lv, S., Zhang, Z., Su, T., Wang, W., Xin, X., Zhao, X., Li, X., Zhang, D., Yu, Y., et al., 2025. Genome assembly of the plant pathogen Plasmodiophora brassicae reveals novel secreted proteins contributing to the infection of Brassica rapa. Hortic. Plant J. 11, 1125-1139.
    Prokchorchik, M., Campbell, M.A., Tobias, P., Downs, J., Choi, S., Kaiser, B.N., 2025. Phylogenomics and effector analysis of Plasmodiophora brassicae genomes unveils a unique and highly divergent clade in Australia. bioRxiv, 2025.07.30.667784.
    Rolfe, S.A., Strelkov, S.E., Links, M.G., Clarke, W.E., Robinson, S.J., Djavaheri, M., Malinowski, R., Haddadi, P., Kagale, S., Parkin, I.A., et al., 2016. The compact genome of the plant pathogen Plasmodiophora brassicae is adapted to intracellular interactions with host Brassica spp. BMC Genomics 17, 272.
    Rouxel, T., Balesdent, M.H., 2017. Life, death and rebirth of avirulence effectors in a fungal pathogen of Brassica crops, Leptosphaeria maculans. New Phytol. 214, 526-532.
    Schwelm, A., Ludwig-Muller, J., 2021. Molecular pathotyping of Plasmodiophora brassicae-genomes, marker genes, and obstacles. Pathogens 10, 259.
    Sedaghatkish, A., Kunz, M., Gossen, B.D., et al., 2026. A contamination-reduced genome of Plasmodiophora brassicae with comprehensive functional annotation. BMC Microbiol. 26, 118.
    Strelkov, S.E., Hwang, S.F., Manolii, V.P., Cao, T., Fredua-Agyeman, R., Harding, M.W., et al., 2018. Virulence and pathotype classification of Plasmodiophora brassicae populations collected from clubroot resistant canola (Brassica napus) in Canada. Can. J. Plant Pathol. 40, 284-298.
    Yadav, A.K., Polasek-Sedlackova, H., 2024. Quantity and quality of minichromosome maintenance protein complexes couple replication licensing to genome integrity. Commun. Biol. 7, 167.
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