Metabolic reprogramming of sucrose flux boosts natural rubber in <i>Taraxacum kok-saghyz</i>

Xiuli Fan; Qingwen Chen; Xiaoguang Song; Liquan Kou; Guodong Wang; Jinfang Chu; Xia Cui; Hong Yu; Xia Xu; Jiayang Li

doi:10.1016/j.jgg.2026.05.009

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Metabolic reprogramming of sucrose flux boosts natural rubber in Taraxacum kok-saghyz

doi: 10.1016/j.jgg.2026.05.009

a. State Key Laboratory of Seed Innovation and National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China;
b. State Key Laboratory of Vegetable Biobreeding, Sino-Dutch Joint Laboratory of Horticultural Genomics, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China;
c. Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable, Ministry of Agriculture and Rural Affairs, College of Horticulture Science, Zhejiang A&F University, Hangzhou, Zhejiang 311300, China;
d. Yazhouwan National Laboratory, Sanya, Hainan 572024, China

Funds:

This work was supported by grants from the National Key Research and Development Program of China (2023YFA0914801), the National Natural Science Foundation of China (31788103, 32200312, 32470390, and 32272061), the Young Elite Scientists Sponsorship Program by CAST (2023QNRC001), and the Strategic Priority Research Program of Chinese Academy of Sciences (XDA24030504).

Received Date: 2026-02-10
Accepted Date: 2026-05-18
Rev Recd Date: 2026-05-17

Available Online: 2026-05-23

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References

Ariyaratne, M., King-Smith, N., and Fresnedo-Ramirez, J., 2023. CRISPR/Cas9-mediated targeted mutagenesis of inulin biosynthesis in rubber dandelion. J. Am. Soc. Hortic. Sci. 148, 266-275.

Chao, J., Wu, S., Shi, M., Xu, X., Gao, Q., Du, H., Gao, B., Guo, D., Yang, S., Zhang, S., et al., 2023. Genomic insight into domestication of rubber tree. Nat. Commun. 14, 4651.

Jayashree, R., Nazeem, P.A., Rekha, K., Sreelatha, S., Thulaseedharan, A., Krishnakumar, R., Kala, R.G., Vineetha, M., Leda, P., Jinu, U., et al., 2018. Over-expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (hmgr1) gene under super-promoter for enhanced latex biosynthesis in rubber tree (Hevea brasiliensis Muell. Arg.). Plant Physiol. Bioch. 127, 414-424.

Kreuzberger M., Hahn T., Zibek S., Schiemann J., and Thiele K., 2016. Seasonal pattern of biomass and rubber and inulin of wild Russian dandelion (Taraxacum koksaghyz L. Rodin) under experimental field conditions. Eur. J. Agron. 80, 66-77.

Panara, F., Lopez, L., Daddiego, L., Fantini, E., Facella, P., and Perrotta, G., 2018. Comparative transcriptomics between high and low rubber producing Taraxacum kok-saghyz R. plants. BMC Genomics 19, 875.

Putter, K.M., van Deenen, N., Unland, K., Prufer, D., and Schulze Gronover, C., 2017. Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway. BMC Plant Biol. 17, 88.

Qin, B., Hou, X., Fan, S., Li, C., Wang, X., Chen, Q., Yang, Y., Lin, P., Lu, L.R., Fu, C., et al., 2025. Simultaneous knockout of Tk1-SST and Tk1-FFT via CRISPR/Cas9 enhances the natural rubber accumulation in Taraxacum kok-saghyz. Plant Biotechnol. J. 23, 5654-5676.

Salehi, M., Cornish, K., Bahmankar, M., and Naghavi, M.R., 2021. Natural rubber-producing sources, systems, and perspectives for breeding and biotechnology studies of Taraxacum kok-saghyz, Ind. Crops Prod. 170, 113667.

Stolze, A., Wanke, A., van Deenen, N., Geyer, R., Prufer, D., and Schulze Gronover, C., 2017. Development of rubber-enriched dandelion varieties by metabolic engineering of the inulin pathway. Plant Biotechnol. J. 15, 740-753.

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