A non-canonical bipartite NLS dictates nuclear import and function of the <i>Drosophila</i> Pc protein

Tao He; Yu Fan; Yongchang Zeng; Jie Zhou; Renjie Jiao; Alan Jian Zhu; Min Liu

doi:10.1016/j.jgg.2025.12.003

A non-canonical bipartite NLS dictates nuclear import and function of the Drosophila Pc protein

doi: 10.1016/j.jgg.2025.12.003

Tao He¹,
Yu Fan²,
Yongchang Zeng¹,
Jie Zhou¹,
Renjie Jiao¹,
Alan Jian Zhu^2,3,4, ,,
Min Liu^2,3, ,

1. Sino-French Hoffmann Institute, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 511436, China;
2. State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China;
3. Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China;
4. Peking University Chengdu Academy for Advanced Interdisciplinary Biotechnologies, Chengdu, Sichuan 610213, China

基金项目:

We thank Dr. Lei Zhang, DSHB, Bloomington Drosophila Stock Center, Tsinghua Fly Center for fly stocks and reagents. We also thank Dr. Chunyan Shan at the National Center for Protein Science at Peking University for assistance with microscopic imaging. This work was supported by National Key Research and Development Program of China (2021YFA0805800 to A.J.Z. and M.L.), National Natural Science Foundation of China (32330026 to A.J.Z., 32170716 to M.L. and 32500731 to T.H.), State Key Laboratory of Membrane Biology (to A.J.Z.), the Peking-Tsinghua Center for Life Sciences (to A.J.Z. and M.L.). Y.F. was supported by a Boya Postdoctoral Fellowship.

详细信息

通讯作者:
Alan Jian Zhu,E-mail:zhua@pku.edu.cn

Min Liu,E-mail:liumin02@pku.edu.cn

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出版历程
- 收稿日期: 2025-09-05
- 录用日期: 2025-12-08
- 修回日期: 2025-12-08
- 网络出版日期: 2025-12-16

A non-canonical bipartite NLS dictates nuclear import and function of the Drosophila Pc protein

Tao He¹,
Yu Fan²,
Yongchang Zeng¹,
Jie Zhou¹,
Renjie Jiao¹,
Alan Jian Zhu^{2,3,4
, ,},
Min Liu^{2,3
, ,}

1. Sino-French Hoffmann Institute, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong 511436, China;
2. State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing 100871, China;
3. Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China;
4. Peking University Chengdu Academy for Advanced Interdisciplinary Biotechnologies, Chengdu, Sichuan 610213, China

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参考文献(20)

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A non-canonical bipartite NLS dictates nuclear import and function of the Drosophila Pc protein

doi: 10.1016/j.jgg.2025.12.003

通讯作者:
Alan Jian Zhu,E-mail:zhua@pku.edu.cn

Min Liu,E-mail:liumin02@pku.edu.cn

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A non-canonical bipartite NLS dictates nuclear import and function of the Drosophila Pc protein

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留言板

A non-canonical bipartite NLS dictates nuclear import and function of the Drosophila Pc protein

doi: 10.1016/j.jgg.2025.12.003

通讯作者: Alan Jian Zhu,E-mail:zhua@pku.edu.cn Min Liu,E-mail:liumin02@pku.edu.cn

计量

出版历程

A non-canonical bipartite NLS dictates nuclear import and function of the Drosophila Pc protein

计量

出版历程

目录

通讯作者:
Alan Jian Zhu,E-mail:zhua@pku.edu.cn

Min Liu,E-mail:liumin02@pku.edu.cn